Pain and Cancer
A plain-language guide to cancer-related pain—what causes it, how a pain control plan works, the types of pain medicine, and non-drug approaches—based on National Cancer Institute resources.
Source: National Cancer Institute · NCI reviewed 2024-06-17 · Verified 2026-07-02
The 30-second version
Having cancer doesn't mean you'll have pain, but if you do, it can usually be controlled with medicine and non-drug approaches. Pain may come from the cancer or from treatment. Your doctor builds a pain control plan that's unique to you. Describing your pain clearly and reporting how the plan is working are key to relief.
Key takeaways
- Having cancer doesn't mean you'll have pain, but if you do, it can usually be controlled.
- Pain may be caused by the cancer itself, by treatments and tests, or by treatment side effects.
- Your doctor develops a pain control plan that is unique to you.
- Don't wait until pain gets bad—the best way to control it is to stop it from starting or getting worse.
- Pain medicines range from over-the-counter drugs to opioids for moderate to severe pain.
- Non-drug approaches like acupuncture, guided imagery, and hypnosis can help too.
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The full explanation.
The simple version
Having cancer doesn't mean that you'll have pain. But if you do, pain can usually be controlled with pain medicine and non-drug approaches. Pain may be caused by the cancer or by cancer treatment.
Controlling pain is an important part of your cancer treatment plan. Treating pain effectively can improve your mood, help you sleep better, and give you energy. Trying to just "deal with" pain can make it harder to control later, so it helps to speak up.
Types and causes of pain
People with cancer may have different types of pain:
- Acute pain may feel sharp, come on quickly, and last only a short time.
- Breakthrough pain comes on suddenly even while you're taking medicine for chronic pain, and usually lasts a short time.
- Chronic pain (also called persistent pain) usually lasts more than three months. It may be mild or severe and may come and go or be constant.
Pain can come from the cancer itself—for example, if a tumor presses on nerves or other parts of the body. Some treatments or tests, such as surgery, cause pain. Pain can also be a side effect of treatment, such as mouth sores, nerve problems, or skin reactions.
Building a pain control plan
Your doctor will develop a plan to control your pain based on your description of it, your symptoms, a physical exam, and sometimes imaging tests. Some hospitals have pain specialists who work as a team, which may include a palliative care specialist, nurse, pharmacist, and others.
Describing your pain clearly helps your team treat it. Be as specific as you can. Your team may ask where the pain is, what it feels like (sharp, burning, shooting, or throbbing), whether it's constant or comes and goes, when it starts and how long it lasts, and how bad it is on a scale of 1 to 10. It also helps to note what makes it better or worse and whether it affects eating, sleeping, or daily activities. Some people track this in a notebook or a phone app.
Contact your doctor or nurse if you feel new pain, if pain isn't decreasing with medicine, or if you have side effects from the medicine.
Taking pain medicine
Different types of pain medicine (also called painkillers, pain relievers, and analgesics) are used to control pain:
- Over-the-counter medicines such as aspirin, acetaminophen, ibuprofen, or naproxen.
- Prescription medicines such as antidepressants, antiseizure medicines, muscle relaxants, or steroids.
- Opioids (also called narcotics) for moderate to severe cancer pain.
Take the prescribed amount at the scheduled time. Don't wait until your pain gets bad—waiting can make it take longer to go away. Tell your doctor if the medicine isn't working, and never stop taking it without talking to your doctor first, since stopping suddenly could cause withdrawal.
Common side effects of pain medicine include constipation, drowsiness, and nausea or vomiting. Some may fade as your body adjusts.
Tolerance, dependence, and addiction
It's common to worry about becoming addicted to pain medicine. It helps to understand three different things:
- Drug tolerance happens when your body gets used to a medicine and it works less well; your doctor may adjust the dose or switch medicines.
- Physical dependence means the body gets used to a certain level of medicine and has symptoms if it's suddenly stopped. This can happen even when a drug is taken as instructed.
- Addiction involves compulsive drug seeking and being unable to stop despite harmful consequences.
Needing a higher dose, or having symptoms when a dose is lowered, is not the same as addiction. Your doctor carefully prescribes and monitors your medicine. Most people with cancer who take strong pain medicine use it safely and effectively.
Non-drug approaches
In addition to medicine, your team may suggest complementary and integrative practices, sometimes called natural pain relief:
- Acupuncture — inserting very thin needles into specific points on the body.
- Biofeedback — learning to control functions like heartbeat and muscle tension.
- Distraction — shifting attention away from pain, such as music or a movie.
- Guided imagery — focusing on positive scenes or experiences.
- Hypnosis — a deeply relaxed, trance-like state.
- Meditation — relaxing the mind and body to improve well-being.
Ask your health care team which of these options might be best for you.
Watch instead
Animated lessons are in production. Here’s the planned video slate for this topic — each one will be based on the same NCI-sourced explanation you’re reading.
Pain and Cancer: the quick overview
A one-breath explanation you can watch before an appointment.
Coming soonPain and Cancer, explained simply
The core ideas with friendly animation and plain language.
Coming soonUnderstanding pain and cancer — full lesson
A deeper walkthrough covering the key takeaways and common questions.
Coming soonVideo transcript▾
A full, readable transcript will appear here when the video is published — so the lesson is accessible whether you prefer to watch, listen, or read. For now, the article above is the complete text version.
Suggested animation storyboard▾
- 1Open on a calm title card: "Pain and Cancer" with the Cancer Explained mark.
- 2Narrator reads the 30-second summary while a soft animated diagram builds on screen: "Having cancer doesn't mean you'll have pain, but if you do, it can usually be controlled with medicine and non-drug approaches. Pain may come from the cancer or from treatment. Your doctor builds a pain control plan that's unique to you. Describing your pain clearly and reporting how the plan is working are key to relief."
- 3Scene 2: illustrate the idea — "Having cancer doesn't mean you'll have pain, but if you do, it can usually be controlled."
- 4Scene 3: illustrate the idea — "Pain may be caused by the cancer itself, by treatments and tests, or by treatment side effects."
- 5Scene 4: illustrate the idea — "Your doctor develops a pain control plan that is unique to you."
- 6Close on a reminder card: this is educational only; talk with your healthcare team, and a link to the NCI source.
Words to know
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Quick knowledge check
According to this article, does having cancer mean you will have pain?
Frequently asked questions
▸Does having cancer mean I will have pain?
No. Having cancer doesn't mean that you'll have pain. But if you do, pain can usually be controlled with pain medicine and non-drug approaches. Pain may be caused by the cancer or by cancer treatment.
▸Why does my doctor want me to take pain medicine on a schedule?
Don't wait until your pain gets bad before taking medicine. If you wait, the pain may take longer to go away, or you may need more medicine. The best way to control pain is to stop it from starting or keep it from getting worse.
▸Should I worry about becoming addicted to pain medicine?
It's common to worry about this. Know that needing a higher dose, or having symptoms when a dose is decreased, is not the same as addiction. Your doctor carefully prescribes and monitors your medicine. Most people with cancer who take strong pain medicine, such as opioids, use them safely and effectively.
▸What's the difference between tolerance, dependence, and addiction?
Drug tolerance is when your body gets used to a medicine and it works less well. Physical dependence is when stopping a drug suddenly causes unpleasant symptoms. Addiction involves compulsive drug seeking and inability to stop despite harm. Tolerance and dependence are not the same as addiction.
▸Can anything besides medicine help my pain?
Yes. Complementary and integrative approaches such as acupuncture, biofeedback, distraction, guided imagery, hypnosis, and meditation may help relieve pain alongside medicine. Ask your health care team which options are best for you.
▸When should I call my doctor about pain?
Contact your doctor or nurse if you feel new pain, if your pain isn't decreasing with medicine, or if you have side effects from the medicine. Pain is not something you have to 'put up with.'
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Questions to ask your healthcare team
Consider bringing these questions to your next appointment.
- What symptoms should I call you about, and which should I go to the emergency room for?
- Which medicine or medicines do you recommend for me?
- What side effects might I have from the pain medicine?
- If the pain doesn't go away, can I take more or take it more often, and how much?
- Is there a pain specialist you could refer me to?
- Are there approaches other than medication that may help my pain?
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