The short answer
Some treatments lower white blood cells (neutropenia), making infections — including from food — more likely and more serious. Safe food handling and, at times, avoiding higher-risk foods like raw or undercooked items and unpasteurized products can lower the risk. Ask your team whether you need extra food precautions right now.
Some treatments lower white blood cells (neutropenia), raising infection risk.
Food safety — clean, separate, cook, chill — matters more when counts are low.
At higher-risk times, teams often advise avoiding raw or undercooked meat, eggs, seafood, and unpasteurized foods.
There is no single strict 'neutropenic diet' proven for everyone; advice varies by center and situation.
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The full explanation.
Why food safety matters when counts are low
Some cancer treatments lower the number of white blood cells that fight infection. That state is called neutropenia. When counts are low, the body has a harder time fighting germs. Infections become more likely and more serious, and that includes food-borne illness, or food poisoning. Extra care with what you eat, and how it is prepared, is one way to lower that risk during the higher-risk stretches of treatment.
The basics: clean, separate, cook, chill
The core food-safety steps help everyone, and they matter more now. Clean: wash your hands, your produce, and your surfaces well. Separate: keep raw meat, poultry, and seafood away from other foods. Cook: cook food all the way through, and use a thermometer for meats where you can. Chill: refrigerate leftovers quickly, and keep cold foods cold. Checking use-by dates and avoiding cross-contamination go a long way.
Foods teams often suggest limiting
During higher-risk periods, care teams commonly advise avoiding a few things. Raw or undercooked meat, poultry, eggs, and seafood are on the list, so sushi and soft-cooked eggs are out. So are unpasteurized milk, juice, and soft cheeses, along with raw sprouts. Wash raw fruits and vegetables well. This is sometimes called a low-microbial or 'neutropenic' diet. Research has not shown that one strict diet fits everyone, and advice differs between cancer centers, so your own team's guidance is what counts.
Ask your team what fits you now
Whether you need extra food precautions depends on your treatment, your blood counts, and your situation. So does how strict they need to be, and it can change over time. Ask your team what they advise for you right now. Tell them about any sign of infection, such as a fever. This page is general background, and your own counts are what should shape the rules you follow.
When to get help sooner
When your white cells are low, an infection can turn serious fast. Do not wait to see if it passes.
- Call your care team immediately, at any hour, if you have a temperature of 100.4°F (38°C) or higher, even with no other symptoms. CDC treats a fever during chemotherapy as a medical emergency, and it needs treatment within hours, not the next day. If you cannot get hold of them quickly, go to an emergency department and say that you are on cancer treatment and your counts may be low.
- Call 911 or go to an emergency department if a fever comes with shaking chills, confusion or heavy drowsiness, shortness of breath, or feeling faint.
- Call your care team the same day if you have vomiting or diarrhea after eating that you cannot control, or you cannot keep fluids down.
- Call your care team within a day or two if you notice new mouth sores, a sore throat, burning when you pass urine, or redness or pain anywhere on your skin.
Ask your team ahead of time which number to call at night and on weekends.
Sources
Words to know
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Common questions
What is neutropenia?
It is a low level of neutrophils, a type of white blood cell that fights infection. Some cancer treatments cause it, which can make infections more likely and more serious.
Is there a strict 'neutropenic diet' I must follow?
Research has not shown one strict diet fits everyone, and advice differs between centers. Good food safety is always sensible; ask your team what extra precautions you need now.
Which foods are higher risk?
Raw or undercooked meat, poultry, eggs, and seafood; unpasteurized milk, juice, and soft cheeses; and raw sprouts. Teams often suggest avoiding these when counts are low.
What are the food-safety basics?
Clean, separate, cook, and chill: wash hands and produce, keep raw meats apart, cook thoroughly, and refrigerate promptly.
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Sources last checked: 2026-08-13 what this meansLast updated: 2026-08-18Next planned review: 2027-07-13
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Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes. We do not employ clinicians and do not intend to — our work is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.
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How this page was created
Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes. We do not employ clinicians and do not intend to — our work is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.
Editorial status: Editorial review complete — This page completed Cancer Explained's editorial checks (sources, safety, plain language, duplication). It has not been reviewed by a physician or other healthcare professional.
Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.
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